Based on Network Pharmacology to Explore the Potential Bioactive Compounds and Mechanisms of Zuojin Pill for the Treatment of Ulcerative Colitis.

Ying Wei Sichen RenRuilin WangManyi JingHonghong LiuMin WangHongtao Song Yan-Ling Zhao

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

ZJP could alleviate UC through the predicted components and mechanisms. The 14 predicted active components of ZJP may mainly play a therapeutic role for UC through synergistic regulation of the PI3K-Akt signaling pathway and MAPK signaling pathway.

Keyphrases

signaling pathway
pi k akt
ulcerative colitis
epithelial mesenchymal transition
induced apoptosis
oxidative stress
cancer therapy
cell proliferation
human health
drug delivery
replacement therapy
climate change