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It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis.

Jason Philip AppletonLisa J WoodhouseAndrew BelcherDaniel BereczkiEivind BergeValeria CasoHui Meng ChangHanne K ChristensenRonan CollinsJohn GommansAnn C LaskaGeorge NtaiosSerefnur OzturkGillian M SareSzabolcs SzatmariYong-Jun WangJoanna M WardlawNikola SpriggPhilip M Bath
Published in: Stroke and vascular neurology (2019)
Following ischaemic stroke, severe ipsilateral carotid stenosis is associated with worse functional outcome at 90 days. GTN appears safe in ipsilateral or bilateral carotid stenosis, and might improve outcome in severe ipsilateral carotid stenosis.
Keyphrases
  • blood pressure
  • early onset
  • heart rate
  • type diabetes
  • hypertensive patients
  • adipose tissue
  • insulin resistance