Role of Silver Nitrate Spray for Skin Wound Care in Patients with Toxic Epidermal Necrolysis: Our Experience in 4 Patients.
José Dario MartínezJesus Alberto CardenasManuel SoriaLuis Manuel SaenzKattya EstradaSergio Maximo DelgadoMarius-Anton IonescuCamelia BusilaAlin Laurențiu TatuPublished in: Life (Basel, Switzerland) (2023)
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of severe cutaneous adverse reactions to drugs (SCARs) with several international recommendations for global medical management, ranging from pharmacological systemic therapy to skin wound care. There is no defined best management of the skin wounds in SJS/TEN. The care of wounds is essential to initiate re-epithelialization. Our objective is to improve the cicatrization process, avoiding scarring due to deepening of the wounds, as well as prevent infections, achieve pain control, and avoid loss of serum proteins, fluids, and electrolytes. In this retrospective case series, we highlight the value of systemic therapy and the use of silver nitrate for wound management in four patients with TEN.
Keyphrases
- wound healing
- healthcare
- palliative care
- quality improvement
- pain management
- nitric oxide
- end stage renal disease
- gold nanoparticles
- soft tissue
- chronic kidney disease
- ejection fraction
- drinking water
- affordable care act
- emergency department
- early onset
- stem cells
- drug induced
- patient reported outcomes
- spinal cord injury
- peritoneal dialysis
- spinal cord
- neuropathic pain
- mesenchymal stem cells
- bone marrow
- patient reported