The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism.

Fang LiuKayla Horton-SparksVanessa HullRobert W LiVeronica Martinez-Cerdeno

Published in: Molecular autism (2018)

Our data on the microbiota of the VPA rat model of autism indicate that this model, in addition to behaviorally and anatomically mimicking the autistic brain as previously shown, also mimics the microbiome features of autism, making it one of the best-suited rodent models for the study of autism and ASD.

Keyphrases

autism spectrum disorder
intellectual disability
attention deficit hyperactivity disorder
endothelial cells
machine learning
multiple sclerosis
brain injury
induced pluripotent stem cells
cerebral ischemia
subarachnoid hemorrhage