Epigenetic findings in periodontitis in UK twins: a cross-sectional study.

Yuko KurushimaPei-Chien TsaiJuan Castillo-FernandezAlexessander Couto AlvesJulia Sarah El-Sayed MoustafaCaroline Le RoyTim D SpectorMark IdeFrancis J HughesKerrin S SmallClaire J StevesJordana T Bell

Published in: Clinical epigenetics (2019)

Epigenome-wide analyses in adult female twins identified specific DNA methylation changes linked to self-reported periodontal disease. Future work will explore the environmental basis and functional impact of these results to infer potential for strategic personalized treatments and prevention of chronic periodontitis.

Keyphrases

dna methylation
genome wide
gene expression
gestational age
human health
current status
physical activity
copy number
risk factors
risk assessment
young adults
drug induced