Cognitive, behavioral, and brain functional connectivity correlates of fatigue in amyotrophic lateral sclerosis.

Francesca TrojsiFederica Di NardoGiulia D'AlvanoCarla PassanitiMinoo SharbafshaaerFabrizio CanaleAntonio RussoMarcello SilvestroLuigi LavorgnaMario CirilloFabrizio EspositoGioacchino TedeschiMattia Siciliano

Published in: Brain and behavior (2023)

Although the "physical" component of fatigue may be influenced by the disease itself, in ALS the "mental" component of fatigue correlates with cognitive and behavioral impairment, as well as with alterations of functional connectivity in extra-motor networks.

Keyphrases

functional connectivity
resting state
sleep quality
mental health
physical activity
white matter