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DIRECTEUR: transcriptome-based prediction of small molecules that replace transcription factors for direct cell conversion.

Momoko HamanoToru NakamuraRyoku ItoYuki ShimadaMichio IwataJun-Ichi TakeshitaRyohei EguchiYoshihiro Yamanishi
Published in: Bioinformatics (Oxford, England) (2024)
The code and data are available at the following link: https://github.com/HamanoLaboratory/DIRECTEUR.git.
Keyphrases
  • single cell
  • transcription factor
  • rna seq
  • electronic health record
  • cell therapy
  • gene expression
  • genome wide
  • big data
  • dna binding
  • dna methylation
  • deep learning