Pru p 3-Glycodendropeptides Based on Mannoses Promote Changes in the Immunological Properties of Dendritic and T-Cells from LTP-Allergic Patients.

Francisca PalomaresJavier Ramos-SorianoFrancisca GomezAinhoa MascaraqueGador BogasJames Richard PerkinsMiguel GonzalezMaria Jose TorresAraceli Diaz-PeralesJavier RojoCristobalina Mayorga

Published in: Molecular nutrition & food research (2019)

Dn ManPrup3 induces changes in DC maturation and lymphocyte proliferation, indicating specific recognition via CLRs. Prup3-GDPs are recognized by immune cells, inducing a specific immune response and modulating the immunological response in FA patients. The specific geometry of D1 ManPrup3 in particular makes it a potential candidate for specific immunotherapy development.

Keyphrases

end stage renal disease
immune response
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
dendritic cells
toll like receptor