Interferon-gamma release assay levels and risk of progression to active tuberculosis: a systematic review and dose-response meta-regression analysis.

Jorge R LedesmaJianing MaPeng ZhengJennifer M RossTheo VosHmwe H Kyu

Published in: BMC infectious diseases (2021)

The current practice of dichotomizing IGRA test results simplifies the TB infection disease continuum. Evaluating IGRA test results over a continuous scale could enable the identification of individuals at greatest risk of progression to active TB.

Keyphrases

mycobacterium tuberculosis
healthcare
primary care
pulmonary tuberculosis
high throughput
dendritic cells
emergency department
immune response
quality improvement
single cell
drug induced