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Effects of oxygen supplementation in autonomic nervous system function during exercise in patients with idiopathic pulmonary fibrosis and exertional desaturation.

Afroditi K BoutouKonstantina DiplaMarieta P TheodorakopoulouKaterina MarkopoulouGeorgia PitsiouStavros PapadopoulosStella KritikouIoannis StanopoulosAndreas Zafeiridis
Published in: The clinical respiratory journal (2021)
IPF patients presented an inadequate adaptive response of their ANS to exercise and recovery. Although oxygen supplementation significantly prolonged exercise duration and prevented the substantial exertional desaturation, the blunted vagal response to steady-state exercise in these patients was not improved, suggesting that acute oxygen supplementation does not sufficiently improve ANS dysfunction in these patients.
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