Integrative omics to detect bacteremia in patients with febrile neutropenia.
Rachel S KellyJessica Lasky-SuSai-Ching J YeungRichard M StoneJeffrey M CaterinoSean C HaganGary H LymanLindsey R BadenBrett E GlotzbeckerChristopher J CoyneChristopher W BaughDaniel J PallinPublished in: PloS one (2018)
Classifiers derived from metabolomic and gene expression data hold promise as objective and accurate predictors of bacteremia among FN patients without apparent infection at presentation, and can provide insights into the underlying biology. Our findings should be considered illustrative, but may lay the groundwork for future biomarker development.