Gastric inhibitory polypeptide/glucose-dependent insulinotropic polypeptide signaling in adipose tissue.

Published in: Journal of diabetes investigation (2018)

GIPR signaling in adipose tissue plays an important role in HFD-induced insulin resistance and hepatic steatosis in vivo, with no direct effect on fat accumulation, through IL-6 signaling.

Keyphrases

adipose tissue
insulin resistance
high fat diet
metabolic syndrome
skeletal muscle
high glucose
polycystic ovary syndrome
oxidative stress
weight loss