Loss of Endothelial Glycocalyx During Normothermic Machine Perfusion of Porcine Kidneys Irrespective of Pressure and Hematocrit.

Tobias M HuijinkCor J van 't HofL Annick van FurthNora A de HaanHanno MaassenLeonie H VenemaRosa G M LammertsMarius C van den HeuvelJan-Luuk HillebrandsJacob van den BornStefan P BergerHenri G D Leuvenink

Published in: Transplantation direct (2023)

NMP is accompanied with eGC and vascular endothelial growth factor receptor-2 loss, without significant loss of endothelial cells. eGC loss was not affected by the different pressures and hematocrits used. It remains unclear whether endothelial injury during NMP has harmful consequences for the transplanted kidney.

Keyphrases

endothelial cells
vascular endothelial growth factor
high glucose
computed tomography
machine learning
magnetic resonance
deep learning
neural network