Influence of CYP2C19 , CYP2D6 , and ABCB1 Gene Variants and Serum Levels of Escitalopram and Aripiprazole on Treatment-Emergent Sexual Dysfunction: A Canadian Biomarker Integration Network in Depression 1 (CAN-BIND 1) Study.
Farhana IslamLeen MagarbehSamar S M ElsheikhStefan KloiberCaroline W EspinolaVenkat BhatBenicio N FreyRoumen MilevClaudio N SoaresSagar V ParikhFranca PlacenzaStefanie HasselValerie H TaylorFrancesco LeriPierre BlierRudolf UherFaranak FarzanRaymond W LamGustavo TureckiJane A FosterSusan RotzingerSidney H KennedyDaniel J MuellerPublished in: Canadian journal of psychiatry. Revue canadienne de psychiatrie (2023)
may help to guide selection of treatment that circumvents selective serotonin reuptake inhibitor-related sexual dysfunction thereby improving outcomes for patients. Additionally, further research is warranted to clarify the role of S-DCT in the mechanisms underlying ESC-related changes in SF and SS. This CAN-BIND-1 study was registered on clinicaltrials.gov (Identifier: NCT01655706) on 27 July 2012.