Association between sacubitril/valsartan initiation and real-world health status trajectories over 18 months in heart failure with reduced ejection fraction.
Merrill ThomasYevgeniy KharitonGregg C FonarowSuzanne V ArnoldLarry HillMichael E NassifPaul S ChanJaved ButlerLaine ThomasAdam D DeVoreAdrian F HernandezNancy M AlbertJ Herbert PattersonFredonia B WilliamsJohn A SpertusPublished in: ESC heart failure (2021)
In outpatient practice, ARNI therapy was associated with improved health status by 3 months and continued to 18 months after initiating therapy.