A Photoreactor-Interfaced Mass Spectrometer: An Online Platform to Monitor Photochemical Reactions.

Oisin J ShielsMaria Menti-PlattenFostino R B BokosiBrett R BurnsSinead T Keaveney Paul A KellerPhilip J BarkerAdam J Trevitt

Published in: Analytical chemistry (2023)

An experimental platform is reported that allows for the online characterization of photochemical reactions by coupling a continuous flow photoreactor, equipped with LED light irradiation and a dual-tipped ESI source, directly to a mass spectrometer with electrospray ionization. The capabilities of this platform are demonstrated with two classes of photoreactions: (1) the photopolymerization of methyl methacrylate and (2) photocatalyzed alkyne insertion into a 1,2,3-benzotriazinone. The online technique provides rapid information to inform the underlying photochemical mechanism and evaluate the overall photochemistry.

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