SAKK 21/12: a phase II trial of transdermal CR1447 in breast cancer patients.
Marcus VetterKarin M RothgiesserQiyu LiHanne HawleWolfgang SchönfeldKarin RibiSalome RinikerRoger von MoosAndreas TrojanElena KralidisMathias FehrAndreas MüllerBeat Thürlimannnull nullPublished in: Endocrine oncology (Bristol, England) (2022)
Despite this trial being negative, the 24% DC24 rate in a second-line setting, and the prolonged partial response experienced by a patient, indicate activity. Further evaluation of CR1447 in endocrine-sensitive patients or combination trials appears warranted.