Dysregulation of the gene signature of effector regulatory T cells in the early phase of systemic sclerosis.
Satomi KobayashiYasuo NagafuchiMai OkuboYusuke SugimoriHiroaki HatanoSaeko YamadaMasahiro NakanoRyochi YoshidaYusuke TakeshimaMineto OtaYumi TsuchidaYukiko IwasakiKeigo SetoguchiKanae KuboTomohisa OkamuraKazuhiko YamamotoHirofumi ShodaKeishi FujioPublished in: Rheumatology (Oxford, England) (2022)
RNA-seq of immune cells indicated the dysregulation of Fr. II eTregs in early SSc with increased proportion of the activated subpopulation.