Tocilizumab Dose Tapering Based on a Model-Based Algorithm is Feasible in Clinical Practice: A Short Communication.

Femke HooijbergZohra LayeghMaureen LeeuwLaura BoekelStefan P H van den BergJill RuwaardCarla BastidaAlwin D R HuitemaSara PelOri ElkayamAnnick de VriesMike NurmohamedTheo RispensThomas P C DorloGertjan Wolbink

Published in: Therapeutic drug monitoring (2024)

This study was the first to show that it is feasible to apply a dose-reduction algorithm based on a pharmacokinetic model in clinical practice. However, the current algorithm needs to be optimized before it can be applied on a larger scale.

Keyphrases

clinical practice
machine learning
deep learning
rheumatoid arthritis
neural network
systemic lupus erythematosus