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Observational study on the prognostic value of testosterone and adiposity in postmenopausal estrogen receptor positive breast cancer patients.

Elisabetta VenturelliAnnalisa OrentiAline S C FabricioGiulia GarroneRoberto AgrestiBiagio PaoliniChiara BoniniMassimo GionFranco BerrinoChristine DesmedtDanila CoradiniElia Biganzoli
Published in: BMC cancer (2018)
In ER-positive postmenopausal breast cancer patients, high testosterone levels are associated with worse prognosis in normal-weight and overweight women, whereas in obese seems to be associated with a better outcome. Although the results require further validation, they suggest that assessment of circulating testosterone and BMI could help to identify postmenopausal ER-positive patients at higher risk of relapse and potentially open new therapeutic strategies.
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