Evaluation of Bone Marrow-derived Stem Cells and Adipose-derived Stem Cells Co-cultured on Human Nucleus Pulposus Cells: A Pilot Study.

Sang Hoon Yoon Dae Hee Kim Sam Cho Ki-Jeong Kim

Published in: Korean journal of neurotrauma (2020)

SA-β-gal staining showed significant attenuation of degenerative changes in NPCs co-cultured with BDMSCs. Moreover, the unexpected increase in LDs was significantly higher in NPCs co-cultured with ADMSCs than in those co-cultured with BDMSCs. However, GAG secretion was significantly decreased in NPCs co-cultured with MSCs.

Keyphrases

endothelial cells
stem cells
mesenchymal stem cells
induced apoptosis
cell cycle arrest
cell death
oxidative stress
endoplasmic reticulum stress