Identification of circulating sphingosine kinase-related metabolites for prediction of type 2 diabetes.

Qi ChenWei WangMing-Feng XiaYou-Li LuHua BianChen YuXiao-Ying LiMathew A VadasXin GaoHuan-Dong Lin Pu Xia

Published in: Journal of translational medicine (2021)

Circulating levels of dhS1P and dhS1P/dhSph ratio are strongly associated with increased risk of T2DM, and could serve as a useful biomarker for prediction of incident T2DM in normoglycemic populations.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
ms ms
tyrosine kinase
protein kinase
metabolic syndrome
adipose tissue
skeletal muscle
genetic diversity