Molecular characterization and drug resistance patterns of Mycobacterium tuberculosis complex in extrapulmonary tuberculosis patients in Addis Ababa, Ethiopia.

Getu Diriba Abebaw KebedeHabteyes Hailu TolaBazezew YenewShewki MogaDesalegn Addise Getahun Ayinalem AlemuZemedu MohammedMuluwork GetahunMengistu FantahunMengistu TadesseBiniyam DagneMisikir AmareGebeyehu Assefa MitikuDessie AberaKassu Desta

Published in: PloS one (2020)

The present study showed a high proportion of MDR-TB and pre-XDR-TB among EPTB patients. The strains were mostly grouped into SIT149, SIT53, and SIT26. The T family lineage was the most prevalent genotype. MDR-TB and pre-XDR-TB prevention is required to combat these strains in EPTB. A large scale study is required to describe the molecular characteristics and drug resistance patterns of MTB isolates in EPTB patients.

Keyphrases

mycobacterium tuberculosis
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
escherichia coli
prognostic factors
emergency department
pulmonary tuberculosis
hiv infected