Back to the Future: Is GnRHa treatment in transgender and gender diverse adolescents only an extended evaluation phase?
Alessandra Daphne FisherJiska RistoriAlessia RomaniEmanuele CassioliFrancesca MazzoliCarlotta CocchettiMarina PierdominiciMatteo MarconiValdo RiccaMario MaggiLinda VignozziGiovanni CastelliniPublished in: The Journal of clinical endocrinology and metabolism (2023)
Psychological improvement in TGDA on GnRHa seems to be related to the objective body changes induced by GnRHa. Therefore, the rationale for treatment with GnRHa may not only be considered an extension of the evaluation phase, but also the start of a medical (even if reversible) gender-affirming path, especially in TGDA whose puberty has already progressed.