A novel WNT10A variant impairs the homeostasis of alveolar bone mesenchymal stem cells.
Bichen LinHaochen LiuHangbo LiuLanxin SuKai SunHailan FengYang LiuMiao YuDong HanPublished in: Oral diseases (2024)
Our findings broaden the spectrum of WNT10A variants in patients with non-syndromic oligodontia, suggest an association between WNT10A and the proliferation and osteogenic differentiation of alveolar bone mesenchymal stem cells, and demonstrate that WNT10A is involved in maintaining jaw bone homeostasis.