High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients.

Tilman Schneider-HohendorfAndreas Schulte-MecklenbeckPatrick OstkampClaudia JanoschkaMarc PawlitzkiFelix LuessiFrauke ZippSven G MeuthLuisa KlotzHeinz WiendlCatharina C GrossNicholas Schwab

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)

High anti-JCPyV indices, which could be indicative of increased viral activity, are associated with elevated immune cell recruitment to the CNS. Its excessive impairment in conjunction with viral activity could predispose for PML development.

Keyphrases

sars cov
end stage renal disease
newly diagnosed
single cell
blood brain barrier
stem cells
cell therapy
physical activity
weight gain
peripheral blood
bone marrow
patient reported outcomes
weight loss