Paradoxical scintigraphy bone scan findings with malignancy-associated extreme hypercalcemia.
Niamh PetersLaura SlatteryClaire CrowleyMichael William BennettJosephine BarrySéamus O'ReillyPublished in: The breast journal (2020)
We report the first case of extreme hypercalcemia (Ca 2+ >6.0 mmol/L) as the initial presentation of de novo metastatic breast cancer. Following treatment and stabilization of the patient, imaging revealed a large breast mass and widespread osseous metastases. Whole body bone scintigraphy demonstrated significant extra osseous uptake of radiotracer in the lungs, liver, and kidneys-a rare phenomenon secondary to profound hypercalcemia. Biopsy revealed estrogen receptor (ER) positive breast carcinoma, for which the patient was treated.
Keyphrases
- estrogen receptor
- metastatic breast cancer
- case report
- bone mineral density
- single cell
- climate change
- high resolution
- soft tissue
- computed tomography
- bone loss
- postmenopausal women
- ultrasound guided
- autism spectrum disorder
- pet imaging
- fine needle aspiration
- magnetic resonance
- newly diagnosed
- replacement therapy
- protein kinase
- smoking cessation