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Comparing the pathology, clinical and demographic characteristics of younger and older-onset multiple sclerosis.

Sarah KnowlesRod MiddletonBenjamin CoozeIldiko FarkasYeung Yeung LeungKelsey AllenMolly WinsladeDavid Rj OwenRoberta MagliozziRichard ReynoldsJames W NealOwen PearsonRichard St John NicholasW Owen PickrellOwain W Howellnull null
Published in: Annals of neurology (2023)
The more progressive nature of older-onset MS is associated with significant neurodegeneration but infrequent inflammatory demyelination. These findings have implications for the assessment and treatment of MS in older people. This article is protected by copyright. All rights reserved.
Keyphrases
  • multiple sclerosis
  • community dwelling
  • white matter
  • middle aged
  • mass spectrometry
  • physical activity
  • ms ms
  • oxidative stress