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Disproportionality Analysis of Stomatitis Associated with Anticancer Drugs Using the Japanese Adverse Drug Event Report Database.

Kousuke HosonakaKenta YamaokaNaoe IkedaMayako UchidaYoshihiro UesawaKazushige TakahashiTadashi Shimizu
Published in: Oncology (2024)
The drugs that may be associated with stomatitis were cell cycle-dependent drugs, epidermal growth factor receptor-tyrosine kinase inhibitors, and mTOR inhibitors. Moreover, this study suggested that anti-growth factor antibodies and immune checkpoint inhibitors may be associated with stomatitis development.
Keyphrases
  • cell cycle
  • adverse drug
  • growth factor
  • epidermal growth factor receptor
  • cell proliferation
  • tyrosine kinase
  • drug induced
  • advanced non small cell lung cancer
  • electronic health record
  • emergency department