Subtyping non-small cell lung cancer by histology-guided spatial metabolomics.

Judith Martha NeumannHinrich FreitagJasmin Saskia HartmannKarsten NiehausMichail GalanisMartin GriesshammerUdo KellnerHanna Bednarz

Published in: Journal of cancer research and clinical oncology (2021)

MALDI-MSI of small molecules can contribute to NSCLC subtyping. Measurements can be performed intraoperatively on a single tissue section to support currently available approaches. Moreover, the technique can be beneficial in screening of IDH-mutants for the characterization of these seldom cases promoting the development of treatment strategies.

Keyphrases

mass spectrometry
small cell lung cancer
wild type
low grade
advanced non small cell lung cancer
high grade
tyrosine kinase