Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion.
Alexander LeatherdaleD'Andra ParkerSubia TasneemYiming WangDominique BihanArkadiusz BonnaSamir W HamaiaPeter L GrossHeyu NiBradley W DobleDavid LillicrapRichard W FarndaleCatherine P M HaywardPublished in: Journal of thrombosis and haemostasis : JTH (2020)
Multimerin 1 supports platelet adhesion and thrombus formation and binds to highly conserved, GPAGPOGPX motifs in fibrillar collagens that synergistically enhance platelet adhesion.