Heterogeneous Photocatalysis of Amoxicillin under Natural Conditions and High-Intensity Light: Fate, Transformation, and Mineralogical Impacts.

The β-Lactam antibiotic amoxicillin is among the most widely used antibiotics in human and veterinary medicine. Consequently, amoxicillin is abundant in natural waters and can undergo diverse abiotic reactions to form degradation compounds under environmental conditions. Yet, little is known about these decay pathways and mineralogical impacts on environmental amoxicillin degradation. The current study focuses on understanding the mineralogical influences of amoxicillin degradation under ecological conditions. We studied the role of anatase and kaolinite on amoxicillin degradation under irradiated and non-irradiated conditions. Anatase increases amoxicillin degradation by 4.5-fold in the presence of light compared to just being exposed to sunlight. Interestingly, anatase also showed a higher degradation rate under dark than light controls. Conversely, kaolinite diminishes the amoxicillin degradation under irradiation. The formation of degradation compounds was mineralogy-controlled, while no mineralization was observed. Further, we irradiated amoxicillin with a high-intensity light to evaluate its removal from wastewater. The formation of varying amoxicillin degradation products with high-intensity light will limit its removal from wastewater. Our study emphasizes that the mineralogical impact on amoxicillin degradation is diverse, and the role of anatase is significant. Consequently, the increased addition of manufactured titanium nanoparticles to the environment can further enhance these effects.