Predictors of radiographic erosion and joint space narrowing progression in patients with early rheumatoid arthritis: a cohort study.

Emil RydellKristina ForslindJan-Åke NilssonMagnus KarlssonKristina E ÅkessonLennart T H JacobssonCarl Turesson

Published in: Arthritis research & therapy (2021)

Overweight RA patients had less JSN progression, independent of smoking status. This effect was seen in particular among older women (mainly post-menopausal), but not younger. Truncal fat was associated with less JSN progression in female patients. Smoking predicted erosion progression, and erosions may precede JSN. BMI and fat distribution may influence cartilage damage in early RA and might be related to hormonal factors.

Keyphrases

rheumatoid arthritis
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
adipose tissue
peritoneal dialysis
disease activity
oxidative stress
body mass index
metabolic syndrome
patient reported outcomes
skeletal muscle
extracellular matrix
drug induced
polycystic ovary syndrome