Broad- and narrow-sense validity performance of three polygenic risk score methods for prostate cancer risk assessment.

Hongjie YuZhuqing ShiXiaoling LinQuanwa BaoHaifei JiaJun WeiBrian T HelfandSiqun L ZhengDavid DugganDaru LuZengnan MoJianfeng Xu

Published in: The Prostate (2019)

The performance of GRS was better than P + T and LDpred. Fewer and well-established SNPs of GRS also make it more feasible and interpretable for genetic testing at the individual level.

Keyphrases

prostate cancer
risk assessment
radical prostatectomy
human health
genome wide
heavy metals