Inhibitor recurrence after immune tolerance induction: a multicenter retrospective cohort study.
A AntunP E MonahanM J Manco-JohnsonMichael J CallaghanM KaninC KnollS L CarpenterJ A DavisM F GuerreraR Kruse-JarresM V RagniC WitmerC E McCrackenC L KemptonPublished in: Journal of thrombosis and haemostasis : JTH (2015)
The use of immune modulation therapy during ITI and lower FVIII recovery at the end of ITI appear to be associated with an increased risk of inhibitor recurrence after successful ITI. Adherence to post-ITI prophylactic FVIII infusions is not a major determinant of recurrence.