Preoperative SPECT/CT + intraoperative CT fusion enabling surgical augmented reality to target sentinel lymph node in endometrial cancer.
Lecointre LiseJuan VerdeFabrice HubeleJulien SalvadoriLaurent GoffinChérif AkladiosBenoît GallixPublished in: EJNMMI physics (2022)
Co-registration and real-time fusion between a preoperative SPECT/CT and intraoperative CT are feasible. The metric performance of our guidance system is excellent in relation to possible SPECT/CT and CT fusion. Based on our results, we are able to translate the technology to patients, and we initiated a clinical study to evaluate the accuracy of the AR guidance system for endometrial cancer surgery, with a correlation with indocyanine green (ICG)-based technique, representing the gold standard today in the intraoperative detection of SLN in endometrial cancers, despite various limitations.
Keyphrases
- endometrial cancer
- image quality
- dual energy
- computed tomography
- contrast enhanced
- sentinel lymph node
- patients undergoing
- positron emission tomography
- magnetic resonance imaging
- lymph node
- end stage renal disease
- pet ct
- early stage
- magnetic resonance
- chronic kidney disease
- squamous cell carcinoma
- ejection fraction
- newly diagnosed
- acute coronary syndrome
- coronary artery bypass
- quantum dots
- patient reported outcomes
- rectal cancer
- locally advanced