The outcomes of relapsed acute myeloid leukemia in children: Results from the Japanese Pediatric Leukemia/Lymphoma Study Group AML-05R study.
Hiroshi MirotakiShiro TanakaTakako MiyamuraHideki NakayamaNorio ShibaAkira ShimadaKiminori TeruiYuki YuzaKatsuyoshi KohHiroaki GotoHarumi KakudaAkiko SaitoDaisuke HasegawaShotaro IwamotoTakashi TagaSouichi AdachiMasanori YoshidaPublished in: Pediatric blood & cancer (2020)
Achieving a CR2 prior to HCT is important in order to improve the prognosis of relapsed pediatric AML. Recent molecular targeted therapies, such as FLT3 inhibitors, may contribute to overcome their prognoses. Larger prospective investigations are necessary to establish individualized treatment strategies for patients with relapsed childhood AML.