Dihydromyricetin inhibits Hepatitis B virus replication by activating NF-κB, MAPKs, and autophagy in HepG2.2.15 cells.

Xuefeng WangHaiming HuBaifei HuHui XiaXue ChengJunping ZhengZhigang ZhangHong-Tao Liu

Published in: Molecular biology reports (2022)

In summary, DHM could suppress HBV replication by activating NF-κB, MAPKs, and autophagy in HepG2.2.15 cells. Our studies shed light on the future application of DHM for the clinical treatment of HBV infection.

Keyphrases

hepatitis b virus
signaling pathway
pi k akt
liver failure
oxidative stress
cell death
endoplasmic reticulum stress
lps induced
current status
immune response
case control