Dengue viral infection in Indonesia: Epidemiology, diagnostic challenges, and mutations from an observational cohort study.
I Made Susila UtamaNurhayati LukmanDewi Dian SukmawatiBachti AlisjahbanaAnggraini AlamDewi MurniatiI Made Gede Dwi Lingga UtamaDwiyanti PuspitasariHerman KosasihIda LaksonoMuhammad KaryanaMulya Rahma KaryantiM M D E A H HapsariNinny MeutiaC Jason LiangWahyu Nawang WulanChuen-Yen LauKetut Tuti Merati ParwatiPublished in: PLoS neglected tropical diseases (2019)
DENV is a common etiology of acute febrile illness requiring hospitalization in Indonesia. Diagnostic accuracy at clinical sites merits optimization since misdiagnosis of DENV infection and over-estimation of dengue can negatively impact management and outcomes. Mutation at the annealing site of the serotyping primer may confound diagnosis. Clinicians should consider following diagnostic algorithms that include DENV confirmatory testing. Policy-makers should prioritize development of laboratory capacity for diagnosis of DENV.
Keyphrases
- dengue virus
- zika virus
- aedes aegypti
- machine learning
- healthcare
- public health
- liver failure
- palliative care
- risk factors
- deep learning
- respiratory failure
- type diabetes
- aortic dissection
- urinary tract infection
- metabolic syndrome
- drug induced
- adipose tissue
- extracorporeal membrane oxygenation
- mechanical ventilation