Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer.
Esmé Ti van der GrachtMark Ja SchoonderwoerdSuzanne van DuikerenAyse N YilmazFelix M BehrJulia M ColstonLian N LeeHideo YagitaKlaas Pjm van GisbergenLukas Jac HawinkelsFrits KoningPaul KlenermanRamon ArensPublished in: Journal for immunotherapy of cancer (2021)
Together, these data show that adenoviral vector-induced CD8+ T cell inflation promotes protective TRM cell populations, and this can be enhanced by targeting CTLA-4.
Keyphrases
- papillary thyroid
- high glucose
- single cell
- diabetic rats
- squamous cell
- electronic health record
- cell therapy
- patient safety
- working memory
- big data
- quality improvement
- drug induced
- endothelial cells
- oxidative stress
- lymph node metastasis
- stem cells
- squamous cell carcinoma
- mesenchymal stem cells
- childhood cancer
- young adults
- stress induced