HIV gp120 in the Lungs of Antiretroviral Therapy-treated Individuals Impairs Alveolar Macrophage Responses to Pneumococci.

Paul J ColliniMartin A BewleyMohamed MohasinHelen M MarriottRobert F MillerAnna-Maria GerettiApostolos BeloukasAthanasios PapadimitropoulosRobert C ReadMahdad NoursadeghiDavid H Dockrell

Published in: American journal of respiratory and critical care medicine (2019)

Despite ART, HIV-1, via gp120, drives persisting innate immune defects in AM microbicidal mechanisms, enhancing susceptibility to pneumococcal disease.

Keyphrases

antiretroviral therapy
hiv infected
hiv positive
human immunodeficiency virus
innate immune
hiv aids
hiv infected patients
hiv testing
men who have sex with men