Andrographolide Attenuates NLRP3 Inflammasome Activation and Airway Inflammation in Exacerbation of Chronic Obstructive Pulmonary Disease.
Yan YuTi-Wei MiaoWei XiaoBing MaoLong-Yi DuYan WangJuan-Juan FuPublished in: Drug design, development and therapy (2024)
AGP effectively inhibited NLRP3 inflammasome activation and mitigated the inflammatory reaction of AECOPD both in animal models and in vitro experiments, highlighting the potential of AGP as a treatment for AECOPD with anti-inflammatory properties.