Lower fetal fraction in clinical cell-free DNA screening results is associated with increased risk of hypertensive disorders of pregnancy.
Deeksha MadalaMohamad Ali MaktabiRiwa SabbaghHadi ErfaniAndrea MoonIgnatia B Van den VeyverPublished in: Prenatal diagnosis (2022)
We found that low FF on cfDNA screening is associated with an increased risk of HDP. Fetal fraction reported that cfDNA screening reports have potential as a predictive marker for the development of HDP and adverse outcomes.