Grey zone amyloid burden affects memory function: the SCIENCe project.

Jarith L EbenauS C J VerfaillieK A van den BoschT TimmersL M P WesselmanM van LeeuwenstijnH TuncelS V S GollaM M YaqubA D WindhorstN D PrinsF BarkhofP ScheltensW M van der FlierB N M van Berckel

Published in: European journal of nuclear medicine and molecular imaging (2020)

We provide evidence that not only high but also grey zone amyloid burden subtly impacts memory function. Therefore, in case a binary classification is required, we suggest using a relatively low threshold which includes grey zone amyloid pathology.

Keyphrases

white matter
working memory
machine learning
public health
deep learning
risk factors
multiple sclerosis