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Pro-BNP Levels and Its Prognostic Role in Chronic Hypertensive Pregnancies: A Prospective Case-Control Study From A Tertiary Care Hospital.

Mehmet Akif ErdolTanacan AtakanHasan ErogluNazan Vanli TonyaliMehmet ErdoganAykan YücelNuray YazihanDilek Şahın
Published in: Hypertension in pregnancy (2021)
Background: This study aimed to investigate the prognostic value of N-terminal B-type natriuretic peptide (NT-proBNP) in pregnancies with isolated chronic hypertension (HT).Method: 34 pregnant women with chronic HT and 40normotensive controls were enrolled. The association between plasma NT-proBNP levels obtained in the first trimester and perinatal complications were evaluated.Results: NT-proBNP levelsstrongly predicted low birth weight (AUC=0.842, p<0.001). NT-proBNP and birth weight were negatively correlated (r= -0.323, p=0.005). NT-proBNP was found to be an individual determinant of low birth weight in univariate analysis (OR:1.03; 95%CI:1.01-1.04).Conclusion: NT-proBNP levels can be useful to predict low birth weight in pregnancies with chronic HT.
Keyphrases
  • low birth weight
  • preterm birth
  • preterm infants
  • human milk
  • gestational age
  • birth weight
  • blood pressure
  • pregnant women
  • weight gain
  • risk factors
  • body mass index
  • drug induced