Genomic correlates of response and resistance to immune checkpoint inhibitors in carcinomas of unknown primary.

Elie Rassy Stergios Boussios Nicholas Pavlidis

Published in: European journal of clinical investigation (2021)

A tumour mutation burden >10 mutations per megabase can provide a potential genomic correlate of response to ICI in patients with CUP. Further research is warranted to validate these findings.

Keyphrases

copy number
high grade
gene expression
human health
genome wide