G721-0282 exerts anxiolytic-like effects on chronic unpredictable mild stress in mice through inhibition of CHI3L1-mediated neuroinflammation.
Hyeon Joo HamYong Sun LeeHee Pom LeeJaesung ChoYoung Wan HamKwang Soo LeeJaesuk YunSang Bae HanJin Tae HongPublished in: British journal of pharmacology (2020)
These results suggest that G721-0282 could lower CUMS-induced anxiety like behaviors by regulating IGFBP3-mediated neuroinflammation via inhibition of CHI3L1.
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