Vitreous and Serum Concentrations of Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor in Proliferative Diabetic Retinopathy.
Habibah Setyawati MuhiddinMuhammad Irfan KamaruddinAndi Muhammad IchsanBudu MannyuPublished in: Clinical ophthalmology (Auckland, N.Z.) (2020)
High concentrations of VEGF and PDGF in vitreous samples of PDR eyes indicate its local related activity in PDR pathology. There is a possibility of PDGF involvement in the pathogenesis of PDR. The VEGF/PDGF concentration ratios possibly play a significant role in the formation of fibrotic tissue in PDR.