Low bone mass and hypovitaminosis D in haemophilia: A single-centre study in patients with severe and moderate haemophilia A and B.

Silvia LinariDaniela MelchiorreLisa PieriLorenzo TofaniAlessandra FanelliMarco BrogiGiancarlo Castaman

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2020)

Low bone mass is a frequent comorbidity in haemophilic patients of all ages, apart from those with MHB. Clinical and laboratory assessments confirm a higher bone impairment and faster bone resorption in HA compared with HB. Looking at H type and severity, MHB seems to have a normal bone metabolism and a less severe disease.

Keyphrases

bone mineral density
bone loss
soft tissue
bone regeneration
end stage renal disease
postmenopausal women
chronic kidney disease
ejection fraction
early onset
newly diagnosed