Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy.

Ida Gjervold LundeJ Magnus AronsenA Olav MellebyMari E StrandJonas SkogestadBård A BendiksenM Shakil AhmedIvar SjaastadHåvard AttramadalCathrine R CarlsonGeir Christensen

Published in: Molecular biology reports (2022)

-dependent calcineurin-NFAT signalling pathway, hypertrophic remodelling and dysfunction in cardiomyocytes in response to pressure overload.

Keyphrases

nuclear factor
high glucose
high fat diet induced
cell proliferation
oxidative stress
transcription factor
angiotensin ii
toll like receptor
type diabetes
adipose tissue
immune response
wild type
insulin resistance